Conference presentations - Umeå universitet

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2 Education, but also stimulating occupational and social 2019-07-23 Cognitive reserve is characterized by a dissociation between cognitive level and brain structure, thereby reducing the impact of deteriorating brain structure on cognitive function. Cognitive reserve is therefore a promising approach to maintaining cognitive function and protecting against symptoms of dementia. The present paper evaluates evidence supporting the claim that bilingualism 2017-03-14 Early‐life factors, such as education, are important for cognitive reserve and those with more education build greater cognitive reserve. Lifelong higher educational attainment also reduces dementia risk.

Cognitive reserve and dementia

The study by Huang and colleagues 2 furthers our understanding in this area and there are now multiple high-quality epidemiological studies linking poorer intelligence in early life with dementia risk. 2020-09-20 · SCD with a high cognitive reserve was related to a lower risk of dementia (OR = 0.50, 95% CI = 0.25–1.00) than SCD with lower cognitive reserve. Relative to low cognitive reserve with SCD, a low grade on the cognitive reserve indicator without SCD was associated with less risk of dementia (OR = 0.31, 95% CI = 0.14–0.68). 2016-08-01 · However, there is substantial heterogeneity in the clinical manifestation of dementia in individuals with similar degrees of brain pathology, which is presumably related to inter-individual differences in cognitive reserve. Cognitive reserve cannot be observed or directly measured, and proxy measures such as education, premorbid intelligence (IQ), linguistic ability, and occupational complexity are often used. Bilingualism may impact on cognitive and neural reserve, time of onset of dementia symptoms and neuropathology, and linguistic competency in dementia.

Preserving Cognitive Reserve Lifestyle choices, achievement of higher Cognitive Reserve and the Prevention of Dementia: the Role of Physical and Cognitive Activities Sheung-Tak Cheng 1,2 # The Author(s) 2016. This article is published with open access at 2018-01-09 Cognitive Reserve has been suggested as the mechanism linking low levels of education with greater risk of neurodegenerative diseases. This reserve, the ability of the brain to better tolerate the effects of a pathology of dementia, may be the result of an innate gift or the effect of life experience, such as education or type of job.

Data to be Presented From Biogen's Alzheimer's Disease

So cognitive reserve really is a concept that we're trying to understand which people use to explain why some people, it seems, are able to maintain a really sort of healthy cognitive ability, despite some of the brain changes that seem to happen that are associated with getting older with aging and with diseases such as Alzheimer's Disease and other forms of dementia. The cognitive reserve is a system that tries to compensate the losses and neuronal atrophies suffered that occur as the person ages.

Data to be Presented From Biogen's Alzheimer's Disease

aging dementia cognitive neuroscience cognitive reserve 9 Dec 2020 In the latest episode of the Aviva Quantum podcast, we talk about increasing our resilience to the effects of dementia. Impact of cognitive reserve in frontotemporal dementia illustrated by FDG-PET. Leonie Beyer, Johanna Meyer-Wilmes, Sonja Schonecker, Jonas Schnabel, Epidemiological research suggests a clear and consistent link of high brain reserve with reduced dementia risk.

Previous studies have demonstrated a paradox: while CR is associated with a delayed symptom onset, The concept of cognitive reserve (CR) posits that once the brain reserve capacity of an individual is depleted past a certain threshold, clinical and functional deficits and symptoms will emerge.
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Bilingualism may impact on cognitive and neural reserve, time of onset of dementia symptoms and neuropathology, and linguistic competency in dementia. This review indicates increased cognitive reserve from executive (monitoring, selecting, inhibiting) control of two languages and increased neural reserve involving left frontal and related areas for language control. David Bennett, MD. A high degree of lifespan cognitive reserve is associated with a reduction in dementia risk, even in the presence of brain pathologies, according to data presented at the 2019 Alzheimer’s Association International Conference, July 14-18, in Los Angeles, California. 1 Cognitive reserve seems to be built from a lifetime exposure to cognitive stimulation. However scientists can’t directly measure or observe this, but they think it induces changes to the structure and function of the brain to make it more resilient and more flexible.

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Whitepaper: Defining and investigating cognitive reserve, brain

Because of its dynamic nature, cognitive reserve might be involved . in future studies as a potential shared antecedent factor for dementia and frailty, and as a novel target of interventions aimed at preventing both cognitive and functional decline in older adults. Objective To examine cross-sectional effects of cognitive reserve (CR) and brain reserve (BR) on cognition across the spectrum of Alzheimer disease (AD). Methods We included 663 AD biomarker–positive participants with dementia (probable AD, n = 462) or in the predementia stages (preclinical/prodromal AD, n = 201). Relative to individuals in the lowest tertile of cognitive reserve indicator, those with moderate and high reserve were at a reduced risk of dementia.

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The concept of cognitive reserve originated in the late 1980s, when researchers described individuals with no apparent symptoms of dementia who were nonetheless found at autopsy to have brain changes consistent with advanced Alzheimer's disease. In this study, we have demonstrated that cognitive reserve is related to dementia prevalence and baseline general and domain-specific cognitive performance in a large cohort of oldest-old participants. However, across a 5-year period, cognitive reserve was not significantly related to incident dementia or trajectories of cognitive performance.

Psychological Medicin e, 29, 1219-1226. The hypothesis behind all these studies of cognitive reserve or brain reserve is that some people’s brains may be more resilient to aging and neurodegeneration than others’. The study by Huang and colleagues 2 furthers our understanding in this area and there are now multiple high-quality epidemiological studies linking poorer intelligence in early life with dementia risk. 2020-09-20 · SCD with a high cognitive reserve was related to a lower risk of dementia (OR = 0.50, 95% CI = 0.25–1.00) than SCD with lower cognitive reserve. Relative to low cognitive reserve with SCD, a low grade on the cognitive reserve indicator without SCD was associated with less risk of dementia (OR = 0.31, 95% CI = 0.14–0.68).